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Troponin I is a part of the troponin complex. It binds to actin in thin myofilaments to hold the troponin-tropomyosin complex in place. The letter I is given due to its inhibitory character.
The tissue specific subtypes are:
- Slow-twitch skeletal muscle isoform troponin I, TNNI1 (1q31.3, 191042)
- Fast-twitch skeletal muscle isoform troponin I, TNNI2 (11p15.5, 191043)
- Cardiac troponin I, TNNI3 (19q13.4, 191044)
External links
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Histology: muscle tissue |
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| skeletal muscle/general |
epimysium, fascicle, perimysium, endomysium, muscle fiber ( intrafusal, extrafusal), myofibril
sarcomere (a, i, and h bands; z and m lines), myofilaments (thin filament/actin, thick filament/myosin, elastic filament/titin, nebulin), tropomyosin, troponin (T, C, I)
costamere (dystrophin, a,ß-dystrobrevin, syncoilin, synemin/desmuslin, dysbindin, sarcoglycan, dystroglycan, sarcospan), desmin
neuromuscular junction, motor unit, muscle spindle, excitation-contraction coupling, sliding filament mechanism
myoblast, satellite cell, sarcoplasm, sarcolemma, sarcoplasmic reticulum, T-tubule
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| cardiac muscle |
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| smooth muscle |
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Proteins of the cytoskeleton |
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| Microfilaments |
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| Intermediate filaments |
type 1 and 2 ( Cytokeratin, type I, type II) - type 3 ( Desmin, GFAP, Peripherin, Vimentin) - type 4 ( Internexin, Nestin, Neurofilament, Synemin, Syncoilin) - type 5 ( Lamin A, B)
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| Microtubules |
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| Catenins |
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| Nonhuman |
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| Other |
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