MK-9470

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MK-9470

IUPAC name	N-((2S,3S)-3-(3-cyanophenyl)-4-(4-ethoxyphenyl)butan-2-yl)-2-methyl-2-(5-methylpyridin-2-yloxy)propanamide
Identifiers
CAS number
PubChem	11167344
SMILES	`C[C@H](N([H])C(C(C)(C)Oc1ncc(C)cc1)=O)[C@@H](Cc2ccc(OCC)cc2)c3cccc(C#N)c3`
Properties
Molecular formula	C₂₉H₃₃N₃O₃
Molar mass	471.59 g/mol
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox references

MK-9470 is a synthetic compound, which binds to the CB₁ cannabinoid receptor and functions as an inverse agonist.^[1]

References

^ Burns HD, Van Laere K, Sanabria-Bohórquez S, Hamill TG, Bormans G, Eng WS, Gibson R, Ryan C, Connolly B, Patel S, Krause S, Vanko A, Van Hecken A, Dupont P, De Lepeleire I, Rothenberg P, Stoch SA, Cote J, Hagmann WK, Jewell JP, Lin LS, Liu P, Goulet MT, Gottesdiener K, Wagner JA, de Hoon J, Mortelmans L, Fong TM, Hargreaves RJ (2007). "[18F]MK-9470, a positron emission tomography (PET) tracer for in vivo human PET brain imaging of the cannabinoid-1 receptor". Proc. Natl. Acad. Sci. U.S.A. 104 (23): 9800–5. doi:10.1073/pnas.0703472104. PMID 17535893.

This article about a cannabinoid is a stub. You can help Wikipedia by expanding it.

v • d • e

Cannabinoids

Plant cannabinoids

CBD • CBDV • CBN • CBG • CBV • CBL • THC • THC-C4 • THCV

Cannabinoid metabolites

11-Hydroxy-THC • 11-nor-9-Carboxy-THC

Endogenous cannabinoids

Arachidonoyl ethanolamide (Anandamide or AEA) • 2-Arachidonoylglycerol (2-AG) • 2-Arachidonyl glyceryl ether (noladin ether) • Virodhamine • N-Arachidonoyl dopamine (NADA) • Oleamide

Synthetic
cannabinoid agonists

Classical cannabinoids (Dibenzopyrans)	A-41988 • Ajulemic acid • AM-087 • AM-411 • AM-855 • AM-905 • AM-906 • AM-919 • AM-938 • AM-4030 • AMG-1 • AMG-3 • AMG-36 • AMG-41 • Dexanabinol (HU-211) • DMHP • Dronabinol • HU-210 • JWH-051 • JWH-133 • JWH-139 • L-759,633 • L-759,656 • Levonantradol • Nabilone • Nabitan • O-806 • O-823 • O-1057 • O-1125 • O-1238 • O-2545 • O-2694 • Parahexyl • THC-O-acetate • THC-O-phosphate

Nonclassical cannabinoids	CP 47,497 • CP 55,244 • CP 55,940 • HU-308 • Nonabine • 2-Isopropyl-5-methyl-1-(2,6-dihydroxy-4-nonylphenyl)cyclohex-1-ene

Aminoalkylindoles	AM-630 • AM-1241 • JWH-007 • JWH-015 • JWH-018 • JWH-073 • JWH-081 • JWH-122 • JWH-200 • JWH-210 • L-768,242 • Pravadoline • WIN 55,212-2

Aminoalkylpyrroles	JWH-030 • JWH-147 • JWH-307

Eicosanoids	AM-883 • Arachidonyl-2'-chloroethylamide • Arachidonylcyclopropylamide • Methanandamide • O-585 • O-689 • O-1812 • O-1860 • O-1861

Others	BAY 38-7271 • BAY 59-3074 • GW-405,833 • GW-842,166X • JWH-171 • O-2220 • Org 28611

Endocannabinoid
activity enhancers

AM-404 • CAY-10401 • CAY-10402 • JZL184 • N-arachidonoyl-serotonin • O-1624 • PF-622 • PF-750 • URB-597 • URB-602 • URB-754

Cannabinoid antagonists
and inverse agonists

AM-251 • AM-281 • AM-630 • BML-190 • CAY-10508 • CB-25 • CB-52 • Drinabant • Ibipinabant • JTE-907 • LY-320,135 • MK-9470 • NESS-0327 • O-1184 • O-1248 • O-2050 • O-2654 • Org 27569 • Otenabant • Rimonabant • SR-144,528 • Surinabant • Taranabant • VCHSR

Categories: Cannabinoid stubs | Cannabinoids | CB1 receptor antagonists

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