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Jun B proto-oncogene, also known as JUNB, is a human gene.[1]
See also
References
Further reading
- Hsu JC, Bravo R, Taub R (1992). "Interactions among LRF-1, JunB, c-Jun, and c-Fos define a regulatory program in the G1 phase of liver regeneration.". Mol. Cell. Biol. 12 (10): 465465. PMID 1406655.
- Zafarullah M, Martel-Pelletier J, Cloutier JM, et al. (1992). "Expression of c-fos, c-jun, jun-B, metallothionein and metalloproteinase genes in human chondrocyte.". FEBS Lett. 306 (2-3): 16972. PMID 1633872.
- Mollinedo F, Vaquerizo MJ, Naranjo JR (1991). "Expression of c-jun, jun B and jun D proto-oncogenes in human peripheral-blood granulocytes.". Biochem. J. 273(Pt 2): 4779. PMID 1899335.
- Nomura N, Ide M, Sasamoto S, et al. (1990). "Isolation of human cDNA clones of jun-related genes, jun-B and jun-D.". Nucleic Acids Res. 18 (10): 30478. PMID 2112242.
- Schόtte J, Viallet J, Nau M, et al. (1990). "jun-B inhibits and c-fos stimulates the transforming and trans-activating activities of c-jun.". Cell 59 (6): 98797. PMID 2513129.
- Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 1714. PMID 8125298.
- Trask B, Fertitta A, Christensen M, et al. (1993). "Fluorescence in situ hybridization mapping of human chromosome 19: cytogenetic band location of 540 cosmids and 70 genes or DNA markers.". Genomics 15 (1): 13345. PMID 8432525.
- Phinney DG, Tseng SW, Ryder K (1996). "Complex genetic organization of junB: multiple blocks of flanking evolutionarily conserved sequence at the murine and human junB loci.". Genomics 28 (2): 22834. doi:10.1006/geno.1995.1135. PMID 8530030.
- Dorsey MJ, Tae HJ, Sollenberger KG, et al. (1996). "B-ATF: a novel human bZIP protein that associates with members of the AP-1 transcription factor family.". Oncogene 11 (11): 225565. PMID 8570175.
- Neyns B, Katesuwanasing , Vermeij J, et al. (1996). "Expression of the jun family of genes in human ovarian cancer and normal ovarian surface epithelium.". Oncogene 12 (6): 124757. PMID 8649827.
- Mendelson KG, Contois LR, Tevosian SG, et al. (1996). "Independent regulation of JNK/p38 mitogen-activated protein kinases by metabolic oxidative stress in the liver.". Proc. Natl. Acad. Sci. U.S.A. 93 (23): 1290813. PMID 8917518.
- Aronheim A, Zandi E, Hennemann H, et al. (1997). "Isolation of an AP-1 repressor by a novel method for detecting protein-protein interactions.". Mol. Cell. Biol. 17 (6): 3094102. PMID 9154808.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 14956. PMID 9373149.
- Fuchs SY, Xie B, Adler V, et al. (1998). "c-Jun NH2-terminal kinases target the ubiquitination of their associated transcription factors.". J. Biol. Chem. 272 (51): 321638. PMID 9405416.
- Venugopal R, Jaiswal AK (1999). "Nrf2 and Nrf1 in association with Jun proteins regulate antioxidant response element-mediated expression and coordinated induction of genes encoding detoxifying enzymes.". Oncogene 17 (24): 314556. doi:10.1038/sj.onc.1202237. PMID 9872330.
- Li B, Tournier C, Davis RJ, Flavell RA (1999). "Regulation of IL-4 expression by the transcription factor JunB during T helper cell differentiation.". EMBO J. 18 (2): 42032. doi:10.1093/emboj/18.2.420. PMID 9889198.
- Liberati NT, Datto MB, Frederick JP, et al. (1999). "Smads bind directly to the Jun family of AP-1 transcription factors.". Proc. Natl. Acad. Sci. U.S.A. 96 (9): 48449. PMID 10220381.
- Chen P, Flory E, Avots A, et al. (2000). "Transactivation of naturally occurring HIV-1 long terminal repeats by the JNK signaling pathway. The most frequent naturally occurring length polymorphism sequence introduces a novel binding site for AP-1 factors.". J. Biol. Chem. 275 (27): 2038290. doi:10.1074/jbc.M001149200. PMID 10764760.
- Echlin DR, Tae HJ, Mitin N, Taparowsky EJ (2000). "B-ATF functions as a negative regulator of AP-1 mediated transcription and blocks cellular transformation by Ras and Fos.". Oncogene 19 (14): 175263. doi:10.1038/sj.onc.1203491. PMID 10777209.
- Verrecchia F, Pessah M, Atfi A, Mauviel A (2000). "Tumor necrosis factor-alpha inhibits transforming growth factor-beta /Smad signaling in human dermal fibroblasts via AP-1 activation.". J. Biol. Chem. 275 (39): 3022631. doi:10.1074/jbc.M005310200. PMID 10903323.
External links
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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Transcription factors and intracellular receptors |
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(1) Basic domains |
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Activating transcription factor ( AATF, 1, 2, 3, 4, 5, 6, 7) AP-1 ( c-Fos, FOSB, FOSL1, FOSL2, c-Jun, JUNB, JUND) BACH ( 1, 2) BATF BLZF1 C/EBP ( a, ί, ?, d, e, ?) CREB ( 1, 3, L1) CREM DBP DDIT3 GABPA HLF MAF ( B, F, G, K) NFE ( 2, L1, L2) NRL NRF1 XBP1
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(1.2) Basic helix-loop-helix ( bHLH)
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ATOH1 AhR AHRR ARNT ASCL1 BHLHB2 BMAL ( ARNTL, ARNTL2) CLOCK EPAS1 HAND ( 1, 2) HES ( 5, 6) HEY ( 1, 2, L) HES1 HIF ( 1A, 3A) ID ( 1, 2, 3, 4) LYL1 MXD4 MYCL1 MYCN Myogenic regulatory factors ( MyoD, Myogenin, MYF5, MYF6) Neurogenins NeuroD ( 1, 2) NPAS ( 1, 2, 3) OLIG ( 1, 2) Scleraxis TAL1 Twist USF1
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(1.4) NF-1
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(1.5) RF-X
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(1.6) Basic helix-span-helix (bHSH)
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(2) Zinc finger DNA-binding domains |
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subfamily 1 ( Thyroid hormone ( a, ί), CAR, FXR, LXR ( a, ί), PPAR ( a, ί/d, ?), PXR, RAR ( a, ί, ?), ROR ( a, ί, ?), Rev-ErbA ( a, ί), VDR)
subfamily 2 ( COUP-TF ( I, II), Ear-2, HNF4 ( a, ?), PNR, RXR ( a, ί, ?), Testicular receptor ( 2, 4), TLX)
subfamily 3 ( Steroid hormone ( Androgen, Estrogen ( a, ί), Glucocorticoid, Mineralocorticoid, Progesterone), Estrogen related ( a, ί, ?))
subfamily 4 NUR ( NGFIB, NOR1, NURR1) subfamily 5 ( LRH-1, SF1) subfamily 6 ( GCNF) subfamily 0 ( DAX1, SHP)
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(2.2) Other Cys4
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(2.3) Cys2His2
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General transcription factors ( TFIIA, TFIIB, TFIID, TFIIE, TFIIF ( 1, 2), TFIIH ( 1, 2, 4, 2I, 3A, 3C1, 3C2))
ATBF1 BCL ( 6, 11A, 11B) CTCF E4F1 EGR ( 2, 3) ERV3 GFI1 GLI-Krόppel family ( 1, 2, 3, S2, YY1) HIC ( 1, 2) HIVEP ( 1, 2, 3) IKZF ( 1, 2, 3) ILF ( 2, 3) KLF ( 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 17 ) MTF1 MYT1 OSR1 SP ( 1, 2, 4, 7) Zbtb7 ( 7A, 7B) ZBTB ( 16, 17, 20, 32, 33, 40) zinc finger ( 3, 7, 9, 10, 19, 22, 24, 33B, 34, 35, 41, 43, 44, 51, 74, 143, 146, 148, 165, 202, 217, 219, 238, 239, 259, 267, 268, 281, 295, 318, 330, 346, 350, 365, 366, 384, 423, 451, 452, 471, 593, 638, 649, 655)
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(2.4) Cys6
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(2.5) Alternating composition
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(3) Helix-turn-helix domains |
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ARX CDX ( 1, 2) CRX CUTL1 DLX ( 3, 4, 5) EMX2 EN ( 1, 2) FHL ( 1, 2, 3) HESX1 HHEX HLX Homeobox ( A1, A3, A4, A5, A7, A9, A10, A11, A13, B1, B2, B3, B4, B5, B6, B7, B8, B9, B13, C4, C5, C6, C8, C9, C10, C11, C13, D1, D3, D4, D8, D9, D10, D11, D12, D13) HOPX MEIS ( 1, 2) MEOX2 MNX1 MSX ( 1, 2) NANOG NKX ( 2-1, 2-2, 2-3, 2-5, 3-1, 3-2) PBX ( 1, 2, 3) PHF ( 1, 3, 6, 8, 10, 16, 17, 20, 21A) PITX ( 1, 2, 3) POU domain ( PIT-1, BRN-3: A, B, C, Octamer transcription factor: 1, 2, 3/4, 6, 7, 11) OTX ( 1, 2) PDX1
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(3.2) Paired box
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E2F ( 1, 2, 3, 4, 5) FOX proteins ( C1, C2, E1, G1, H1, K2, L2, M1, N3, O1A, O3A, O4, P1, P2, P3)
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(3.5) Tryptophan clusters
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ELF ( 4, 5) EGF ELK ( 1, 3, 4) ERF ERG ETS ( 1, 2, SPIB) ETV ( 1, 4, 5, 6) FLI1 Interferon regulatory factors ( 1, 2, 3, 4, 5, 6, 7, 8) MYB MYBL2
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(3.6) TEA domain
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transcriptional enhancer factor 1, 2
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(4) ί-Scaffold factors with minor groove contacts |
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(4.1) Rel homology region
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(4.3) p53
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HMGB ( 1, 2, 3) HNF ( 1A, 1B) LEF1 SOX ( 2, 3, 4, 5, 6, 8, 9, 10, 11, 12, 13, 14, 15, 18, 21) SRY SSRP1 TOX ( 1, 2, 3, 4)
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(4.10) Cold-shock domain
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(4.11) Runt
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(0) Other transcription factors |
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(0.2) HMGI(Y)
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(0.6) Miscellaneous
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ARID ( 1A, 1B, 2, 3A, 3B, 4A) CAP IFI ( 16, 35) MLL ( 2, 3, T1) MNDA NFI ( A, B, C, X) NFY ( A, B, C) Rho/ Sigma R-SMAD
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