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Glycolipid transfer protein is a cytosolic protein that catalyses the transfer of glycolipids between different intracellular membranes. [1][2].
This protein transport primarily different glycosphingolipids and glyceroglycolipids between intracellular membranes, but not phospholipids. It might be also involved in translocation of glucosylceramides. It was found in brain, kidney, spleen, lung, cerebellum, liver and heart.
Human proteins containing this domain
GLTP; PLEKHA8; PLEKHA9;
References
- ^ Brown RE, Lin X, Rao CS, Pike HM, Molotkovsky JG (2004). "Glycolipid transfer protein mediated transfer of glycosphingol ipids between membranes: a model for action based on kinetic and thermodynamic analyses". Biochemistry 43 (43): -. doi:10.1021/bi0492197. PMID 15504043.
- ^ Nymalm Y, Airenne TT, Kidron H, Salminen TA, Nylund M, West G, Mattjus P (2006). "Structural evidence for adaptive ligand binding of glycolipid transfer protein". J. Mol. Biol. 355 (2): -. PMID 16309699.
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